Lung cancer is the leading cause of cancer death worldwide and even today only 10% of people survive lung cancer for 10 years or more in the UK. One challenge in treating lung cancer is that lung ...
p21 interacts with Zbtb18 to co-repress the transcription of cKit in HSCs, contributing to the enhanced self-renewal ability of p21-tdT + HSCs. The study provides novel insights into the physiological ...
Ubiquitin-specific protease 7 (USP7) is involved in DNA repair and cell cycle progression and, due to its control over the ubiquitination of key proteins, may impact oncogenes like MDM2 and c-Myc, as ...
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