A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water. For most treatments, the oral route remains the gold ...

Hydrogels are among the most widely studied biomaterials in modern drug delivery research. Their high hydrophilicity, ...

A recent study shows that computer algorithms can be used to find molecules that can be developed into anti-inflammatory drugs. In the article, the researchers also describe how the same strategy can ...

Raghab Singh’s research advances structure-first AI models for healthcare, combining molecular geometry and language ...

Fluorine is critical for biomedicine. This element can help drug compounds be more potent and last longer in the body, and its radioactive isotope, fluorine-18, powers medical imaging techniques such ...

As the science of drug discovery has grown in scale and gotten more complicated, so have the drug molecules themselves. But there’s a promising class of drugs made of just a handful of atoms that ...

A version of this story appeared in Volume 101, Issue 36 Not too long ago, these small-molecule drugs looked as if they were going out of fashion. Advances in biotechnology enabled pharmaceutical ...