Codon usage varies widely between species, between genes in a genome and between sites in a gene. Explanations for natural variation in codon usage fall into two categories: mutational and selective.
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
The other known alternate sense codon use among yeast was first identified in Candida albicans two decades ago. This too involves a CUG codon, but results in serine in the translated protein. “For ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes long-standing trade-offs between maximizing expression metrics and maintaining ...