Proteins are the molecular machines of cells. They are produced in protein factories called ribosomes based on their blueprint—the genetic information. Here, the basic building blocks of proteins, ...

Recently identified and long-lasting type of protein misfolding — non-native entanglements — observed in all-atom protein folding simulations. Representative misfolded conformations of the small ...

Neurodegenerative diseases like Alzheimer's disease or Parkinson's disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure. This is the ...

Aisha Burton is a Postdoctoral Research Fellow at the National Institutes of Health (NIH; MD, USA), where her research focuses on characterizing small proteins to understand regulatory mechanisms, ...

Chemobiological screening for identification of molecular targets for thymic epithelial cancers. Background: The importance of definitive histologic subclassification has significantly increased as ...

Producing functional membrane proteins remains a major hurdle in both drug discovery and structural biology. While these proteins are central to cellular signaling and serve as key therapeutic targets ...