A new in vivo pharmacokinetic recall study involving 114 participants in the Estonian Biobank has provided the first clinical ...
A study based on data from the Estonian Biobank shows that previously unstudied genetic variants may slow the breakdown of medications, leading to their buildup in the body. The risk of side effects ...
A graphical summary illustrates the strategy used to identify CYP2D6 as a target for collateral lethality, which is driven by the widespread occurrence of loss of heterozygosity in cancer genomes.
The human genome is organised in 46 chromosomes, where all but the x and y chromosomes in men are present in two copies. This means that a person with a faulty gene on one chromosome most often has a ...
Tamoxifen reduces the rate of breast cancer recurrence by approximately a half. Tamoxifen is metabolized to more active metabolites by enzymes encoded by polymorphic genes, including cytochrome P450 ...
June 7 -- FRIDAY, June 6 (HealthDay News) -- The popular painkiller codeine can be ineffective or, worse, cause serious reactions if you are among those people whose bodies do not process the ...
The human genome is organised in 46 chromosomes, where all but the x and y chromosomes in men are present in two copies. This means that a person with a faulty gene on one chromosome most often has a ...
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