A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast ...

Explore new findings on drug-resistant breast cancer and how targeting cell cycle regulators may improve treatment outcomes.

Most genes known to control the cell cycle are mutated in cancer, some of them quite frequently. These include famous genes such as K-ras and p53. One notable exception is the cyclin-dependent kinase ...

This preclinical study explains the mechanism underlying CDK2 and CDK4/6 combination therapy, providing a blueprint for future clinical use These findings are notable because several CDK2 inhibitor ...