In patients with NSTE-ACS on heparin monotherapy during PCI, lower activated clotting time (ACT) values do not predict bleeding events but do correlate with higher risk of ischemic events, according ...

Drug resistance is defined as the lack of expected response to a standard therapeutic dose of a drug or as resistance resulting from biologic changes in the target, as occurs in antibiotic resistance.

Credit: Shutterstock. Researchers related maximal ACT to the risk of major bleeding in 14,634 patients undergoing TR or TF PCI with unfractionated heparin monotherapy. HealthDay News — Higher maximal ...

During big procedures like open heart surgery, patients need anticoagulants to prevent dangerous blood clot formation and regular bedside monitoring to make sure the drugs aren't also causing problems ...

The ROTEM system is a point‑of‑care device used to help detect, manage and monitor haemostasis associated with high blood loss. The device uses thromboelastometry, a viscoelastometric method, to test ...